Analysis of fMRI Timeseries: Linear Time-Invariant Models, Event-related fMRI and Optimal Experimental Design

Event-related fMRI contrast when using constant interstimulus interval: theory and experiment.

Event-related functional magnetic resonance imaging (ER-fMRI) involves the mapping of averaged hemodynamic changes resulting from repeated, brief (<3 sec) brain activation episodes. In this paper, two issues regarding constant-interstimulus interval ER-fMRI were addressed. First, the optimal interstimulus interval (ISI), given a stimulus duration (SD), was determined. Second, the statistical po...

Linear Models for Event - Related fMRI TimeSeries with Overlapping

Feature selection using genetic algorithm for classification of schizophrenia using fMRI data

In this paper we propose a new method for classification of subjects into schizophrenia and control groups using functional magnetic resonance imaging (fMRI) data. In the preprocessing step, the number of fMRI time points is reduced using principal component analysis (PCA). Then, independent component analysis (ICA) is used for further data analysis. It estimates independent components (ICs) of...

Analysis of Resting-State fMRI Topological Graph Theory Properties in Methamphetamine Drug Users Applying Box-Counting Fractal Dimension

Introduction: Graph theoretical analysis of functional Magnetic Resonance Imaging (fMRI) data has provided new measures of mapping human brain in vivo. Of all methods to measure the functional connectivity between regions, Linear Correlation (LC) calculation of activity time series of the brain regions as a linear measure is considered the most ubiquitous one. The strength of the dependence obl...

An Introduction to fMRI

Functional magnetic resonance imaging (fMRI) provides an opportunity to indirectly observe neural activity noninvasively in the human brain as it changes in near real time. Most fMRI experiments measure the blood oxygen-level dependent (BOLD) signal, which rises to a peak several seconds after a brain area becomes active. Several experimental designs are common in fMRI research. Block designs a...